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Biological Activity
PF-04217903 is a novel c-Met/hepatocyte growth factor receptor tyrosine kinase inhibitors.
Targets
c-Met (A549 cells) | ||||
4.8 nM |
In vitro (25°C) | DMSO | 5 mg/mL (13.42 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 1 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 26.85 mL | 134.26 mL | 268.53 mL |
0.5 mM | 5.37 mL | 26.85 mL | 53.71 mL |
1 mM | 2.69 mL | 13.43 mL | 26.85 mL |
5 mM | 0.54 mL | 2.69 mL | 5.37 mL |
*The above data is based on the productmolecular weight 372.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A10711 |
---|---|
Actions | Inhibitor |
CAS No. | 956905-27-4 |
Formula | C19H16N8O |
M. Wt | 372.4 |
Purity | >98% |
Synonyms | PF04217903 |
SMILES | C1=CC2=C(C=CC(=C2)CN3C4=NC(=CN=C4N=N3)C5=CN(N=C5)CCO)N=C1 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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