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Catalog No.: A10711

c-Met Inhibitor


PF-04217903 Chemical Structure

CAS NO. 956905-27-4

PF-04217903 is a novel c-Met/hepatocyte growth factor receptor tyrosine kinase inhibitors.

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Biological Activity

PF-04217903 is a novel c-Met/hepatocyte growth factor receptor tyrosine kinase inhibitors.
c-Met (A549 cells)
4.8 nM
In vitro (25°C) DMSO 5 mg/mL (13.42 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.85 mL 134.26 mL 268.53 mL
0.5 mM 5.37 mL 26.85 mL 53.71 mL
1 mM 2.69 mL 13.43 mL 26.85 mL
5 mM 0.54 mL 2.69 mL 5.37 mL

*The above data is based on the productmolecular weight 372.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10711
Actions Inhibitor
CAS No. 956905-27-4
Formula C19H16N8O
M. Wt 372.4
Purity >98%
Synonyms PF04217903

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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