PF-06250112

Catalog No.: A18612
BTK inhibitor
PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC50 of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC50s of 0.9 nM and 1.2 nM, respectively.
Grouped product items
Product Name Price Stock Qty
PF-06250112 5mg
$140.00
In stock
PF-06250112 10mg
$240.00
In stock
PF-06250112 50mg
$920.00
In stock
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Biological Activity
Discription PF-06250112 is a potent, highly selective, orally bioavailable BTK inhibitor with an IC50 of 0.5 nM, shows inhibitory effect toward BMX nonreceptor tyrosine kinase and TEC with IC50s of 0.9 nM and 1.2 nM, respectively.
Product Information
Catalog Num A18612
Formula C22H20F2N6O2
Molecular Weight 438.43
CAS Number 1609465-89-5
SMILES O=C(N)C1=C(N(N=C1C2=CC=C(C=C2)OC3=CC=C(C=C3F)F)[C@@H]4CN(CCC4)C#N)N
Synonyms PF06250112, PF 06250112
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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