PF-4618433

Catalog No.: A13461

PYK2/FAK inhibitor

PF-4618433

PF-4618433 Chemical Structure

CAS NO. 1166393-85-6

PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796.

Availability: In stock

Package Price Qty
5 mg
$300.00
10 mg
$520.00
25 mg
$1,100.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-4618433 shows improved PYK2 potency, reduced p38 activity, and superior overall selectivity relative to the prototype BIRB796.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.45 mL 112.23 mL 224.46 mL
0.5 mM 4.49 mL 22.45 mL 44.89 mL
1 mM 2.24 mL 11.22 mL 22.45 mL
5 mM 0.45 mL 2.24 mL 4.49 mL

*The above data is based on the productmolecular weight 445.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13461
Actions Inhibitor
M. Wt 445.52
Formula C24H27N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1166393-85-6
Synonyms PF 4618433, PF4618433
SMILES Cc1ccc(cc1)n2c(cc(n2)C(C)(C)C)NC(=O)Nc3cc(n[nH]3)COc4cccnc4

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