PF-543

Catalog No.: A13039

SphK1 inhibitor

PF-543

PF-543 Chemical Structure

CAS NO. 1415562-82-1

PF-543 is a novel selective SK-1 inhibitor which inhibited SK-1 activity in a competitive manner with sphingosine.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $150.00

Special Price $135.00

25 mg

Regular Price: $300.00

Special Price $270.00

50 mg

Regular Price: $500.00

Special Price $450.00

10mM * 1mL in DMSO

Regular Price: $129.00

Special Price $116.10

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-543 is a novel selective SK-1 inhibitor which inhibited SK-1 activity in a competitive manner with sphingosine.
Targets
SphK1 SphK1
2.0 nM3.6 nM(Ki)
In vitro DMSO 93 mg/mL (199.74 mM)
Water <1 mg/mL (<1 mM)
Ethanol 93 mg/mL (199.74 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.48 mL 107.39 mL 214.78 mL
0.5 mM 4.3 mL 21.48 mL 42.96 mL
1 mM 2.15 mL 10.74 mL 21.48 mL
5 mM 0.43 mL 2.15 mL 4.3 mL

*The above data is based on the productmolecular weight 465.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13039
Actions Inhibitor
M. Wt 465.6
Formula C27H31NO4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1415562-82-1
Synonyms PF543,PF 543
SMILES CC1=CC(=CC(=C1)OCC2=CC=C(C=C2)CN3CCC[[email protected]@H]3CO)CS(=O)(=O)C4=CC=CC=C4

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