PLX5622

Catalog No.: A18888
CSF1R inhibitor
PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor with an Ki of 5.9 nM, for extended and specific microglial elimination, preceding and during pathology development.
Grouped product items
Size Price Stock Qty
2mg
$50.00
In stock
5mg
$100.00
In stock
10mg
$170.00
In stock
50mg
$580.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's PLX5622 has been cited by 1 publications
  • Ilija Brizic, .et al. , Research Square, 2024, October 3rd
  • Biological Activity
    Discription PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor with an Ki of 5.9 nM, for extended and specific microglial elimination, preceding and during pathology development.
    Product Information
    Catalog Num A18888
    Formula C21H19F2N5O
    Molecular Weight 395.41
    CAS Number 1303420-67-8
    SMILES COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2
    Synonyms PLX 5622, PLX-5622
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 71 mg/mL (179.56 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 25.29 mL 126.45 mL 252.9 mL
    0.5 mM 5.06 mL 25.29 mL 50.58 mL
    1 mM 2.53 mL 12.65 mL 25.29 mL
    5 mM 0.51 mL 2.53 mL 5.06 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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