PLX5622

Catalog No.: A18888

CSF1R inhibitor

PLX5622

PLX5622 Chemical Structure

CAS NO. 1303420-67-8

PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor with an Ki of 5.9 nM, for extended and specific microglial elimination, preceding and during pathology development.

Availability: In stock

Package Price Qty
2 mg
$50.00
5 mg
$100.00
10 mg
$170.00
50 mg
$580.00
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Biological Activity

PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor with an Ki of 5.9 nM, for extended and specific microglial elimination, preceding and during pathology development.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.29 mL 126.45 mL 252.9 mL
0.5 mM 5.06 mL 25.29 mL 50.58 mL
1 mM 2.53 mL 12.65 mL 25.29 mL
5 mM 0.51 mL 2.53 mL 5.06 mL

*The above data is based on the productmolecular weight 395.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18888
Actions Inhibitor
M. Wt 395.41
Formula C21H19F2N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1303420-67-8
Synonyms PLX 5622, PLX-5622
SMILES COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2

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