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Biological Activity
PLX647 is a highly specific dual FMS/KIT kinase inhibitor with IC50 of 28/16 nM respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.15 mL | 130.76 mL | 261.52 mL |
| 0.5 mM | 5.23 mL | 26.15 mL | 52.3 mL |
| 1 mM | 2.62 mL | 13.08 mL | 26.15 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.23 mL |
*The above data is based on the productmolecular weight 382.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15519 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 873786-09-5 |
| Formula | C21H17F3N4 |
| M. Wt | 382.38 |
| Purity | >98% |
| Synonyms | PLX-647, PLX 647 |
| SMILES | C1=CC2=C(NC=C2CC3=CN=C(C=C3)NCC4=CC=C(C=C4)C(F)(F)F)N=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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