Catalog No.: A13140

FAK inhibitor


PND-1186 Chemical Structure

CAS NO. 1061353-68-1

PND-1186 is a potent FAK inhibitor with IC50 of 1.5 nM.

Availability: In stock

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5 mg
10 mg
25 mg
10mM * 1mL in DMSO
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Biological Activity

PND-1186 is a potent FAK inhibitor with IC50 of 1.5 nM.
0.5 nM
In vitro (25°C) DMSO 22 mg/mL (43.86 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13140
Actions Inhibitor
CAS No. 1061353-68-1
Formula C25H26F3N5O3
M. Wt 501.5
Purity >98%
Synonyms SR-2516, PND 1186, PND1186, SR 2516, SR2516

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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