PND-1186

Catalog No.: A13140

FAK inhibitor

PND-1186

PND-1186 Chemical Structure

CAS NO. 1061353-68-1

PND-1186 is a potent FAK inhibitor with IC50 of 1.5 nM.

Availability: In stock

Package Price Qty
5 mg
$110.00
10 mg
$150.00
25 mg
$340.00
10mM * 1mL in DMSO
$121.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PND-1186 is a potent FAK inhibitor with IC50 of 1.5 nM.
Targets
FAK
0.5 nM
In vitro DMSO 24 mg/mL (47.85 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13140
Actions Inhibitor
M. Wt 501.5
Formula C25H26F3N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1061353-68-1
Synonyms SR-2516, PND 1186, PND1186, SR 2516, SR2516
SMILES CNC(=O)C1=CC=CC=C1NC2=CC(=NC=C2C(F)(F)F)NC3=C(C=C(C=C3)N4CCOCC4)OC

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