Poseltinib (HM71224, LY3337641)

Name: Poseltinib (HM71224, LY3337641)
Brand: Adooq Bioscience
SKU: A19450
Rating: 5 (288 reviews)

Catalog No.: A19450

BTK inhibitor

Poseltinib, an orally active, selective and irreversible Bruton??s tyrosine kinase (BTK) inhibitor (IC50 =1.95 nM), with 0.3, 2.3 and 2.4-fold selectivity for BTK over BMX, TEC and TXK, respectively.

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Poseltinib (HM71224, LY3337641) 1353552-97-2 BTK inhibitor

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Grouped product items
Size	Price	Stock
1mg	$20.00	In stock
2mg	$30.00	In stock
5mg	$50.00	In stock
10mg	$90.00	In stock
50mg	$360.00	In stock
100mg	$570.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description

Poseltinib, an orally active, selective and irreversible Bruton??s tyrosine kinase (BTK) inhibitor (IC50 =1.95 nM), with 0.3, 2.3 and 2.4-fold selectivity for BTK over BMX, TEC and TXK, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A19450
Formula	C26H26N6O3
Molecular Weight	470.52
CAS Number	1353552-97-2
SMILES	O=C(C=C)NC1=CC=CC(OC2=C(OC=C3)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=N2)=C1
Synonyms	HM 71224, HM-71224, LY-333764, LY 33376411
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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