PROTAC MDM2 Degrader-4

Catalog No.: A18877

MDM2 inhibitor

PROTAC MDM2 Degrader-4

PROTAC MDM2 Degrader-4 Chemical Structure

CAS NO. 2249750-24-9

PROTAC MDM2 Degrader-4 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-4 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase.

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

PROTAC MDM2 Degrader-4 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-4 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 7.18 mL 35.89 mL 71.78 mL
0.5 mM 1.44 mL 7.18 mL 14.36 mL
1 mM 0.72 mL 3.59 mL 7.18 mL
5 mM 0.14 mL 0.72 mL 1.44 mL

*The above data is based on the productmolecular weight 1393.19. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18877
Actions Inhibitor
CAS No. 2249750-24-9
Formula C70H74Cl4N8O14
M. Wt 1393.19
Purity >98%
Synonyms 0
SMILES O=C(N1CC(N(CC(OCCOCCOCCOC(CN2C(CN(C(N3[[email protected]](C4=CC=C(Cl)C=C4)[[email protected]](C5=CC=C(Cl)C=C5)N=C3C6=C(C=C(OC)C=C6)OC(C)C)=O)CC2)=O)=O)=O)CC1)=O)N7[[email protected]](C8=CC=C(Cl)C=C8)[[email protected]](C9=CC=C(Cl)C=C9)N=C7C%10=C(C=C(OC)C=C%10)OC(C)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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