Catalog No.: A15524

Syk inhibitor


PRT-060318 Chemical Structure

CAS NO. 1194961-19-7

PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach to HIT treatment.

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Biological Activity

PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach to HIT treatment.
In vitro (25°C) DMSO 66 mg/mL (159.67 mM)
Water 66 mg/mL (159.67 mM)
Ethanol Insoluble
In vivo water 71 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.38 mL 146.88 mL 293.75 mL
0.5 mM 5.88 mL 29.38 mL 58.75 mL
1 mM 2.94 mL 14.69 mL 29.38 mL
5 mM 0.59 mL 2.94 mL 5.88 mL

*The above data is based on the productmolecular weight 340.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15524
Actions Inhibitor
CAS No. 1194961-19-7
Formula C18H24N6O
M. Wt 340.42
Purity >98%
Synonyms PRT 060318, PRT060318, PRT318, P142?C76.

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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