PT-2385
Catalog No.: A21561
HIF-2α inhibitor
PT-2385 is a selective HIF-2α inhibitor with a Ki of less than 50 nM.
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Biological Activity
| Description | PT-2385 is a selective HIF-2α inhibitor with a Ki of less than 50 nM. |
|---|
Product Information
| Catalog Num | A21561 |
|---|---|
| Formula | C17H12F3NO4S |
| Molecular Weight | 383.34 |
| CAS Number | 1672665-49-4 |
| SMILES | N#CC1=CC(F)=CC(OC2=CC=C(S(=O)(C)=O)C3=C2CC(F)(F)[C@H]3O)=C1 |
| Synonyms | PT 2385, PT2385 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 74 mg/mL (193.03 mM) | |
| Water | Insoluble | ||
| Ethanol | 5 mg/mL (13.04 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.09 mL | 130.43 mL | 260.87 mL |
| 0.5 mM | 5.22 mL | 26.09 mL | 52.17 mL |
| 1 mM | 2.61 mL | 13.04 mL | 26.09 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.22 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
