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QL47B

Catalog No.: A34422
BTK Inhibitor
QL47B is a biotinylated inhibitor of Bruton's tyrosine kinase (BTK), exhibiting a potent inhibitory effect with an IC50 value of 1.3 μM. This compound demonstrates significant anti-tumor activity, making it valuable for research in cancer therapeutics and cellular signaling pathways involving BTK modulation. Its biotinylation allows for easy detection in experimental settings, enhancing its utility in biochemical assays and studies of BTK-related mechanisms.
QL47B 1579278-92-4 BTK Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionQL47B is a biotinylated inhibitor of Bruton's tyrosine kinase (BTK), exhibiting a potent inhibitory effect with an IC50 value of 1.3 μM. This compound demonstrates significant anti-tumor activity, making it valuable for research in cancer therapeutics and cellular signaling pathways involving BTK modulation. Its biotinylation allows for easy detection in experimental settings, enhancing its utility in biochemical assays and studies of BTK-related mechanisms.
Product Information
Catalog NumA34422
FormulaC46H55N9O7S
Molecular Weight878.05
CAS Number1579278-92-4
SMILESO=C1N(C2=C(C=C1)C=NC3=CC=C(C4=CN(C)N=C4)C=C32)C5=CC=C6C(N(C(/C=C/CNCCOCCOCCOCCNC(CCCC[C@H]7[C@](NC(N8)=O)([H])[C@]8([H])CS7)=O)=O)CC6)=C5
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Angiogenesis > BTK