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Radotinib is a novel and selective Bcl-Abl tyrosine kinase inhibitor
Targets
| BCR-ABL1 | ||||
| 34 nM |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.85 mL | 94.25 mL | 188.5 mL |
| 0.5 mM | 3.77 mL | 18.85 mL | 37.7 mL |
| 1 mM | 1.89 mL | 9.43 mL | 18.85 mL |
| 5 mM | 0.38 mL | 1.89 mL | 3.77 mL |
*The above data is based on the productmolecular weight 530.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A13029 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 530.5 |
| Formula | C27H21F3N8O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 926037-48-1 |
| Synonyms | IY-5511 |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=NC=CN=C5 |
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