Radotinib (IY-5511)

Catalog No.: A13029

Bcr-Abl tyrosine inhibitor‎

Radotinib (IY-5511)

Radotinib (IY-5511) Chemical Structure

CAS NO. 926037-48-1

Radotinib is a novel and selective Bcl-Abl tyrosine kinase inhibitor

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$210.00
50 mg
$320.00
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Biological Activity

Radotinib is a novel and selective Bcl-Abl tyrosine kinase inhibitor
Targets
BCR-ABL1
34 nM
In vitro DMSO 94 mg/mL (177.19 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.85 mL 94.25 mL 188.5 mL
0.5 mM 3.77 mL 18.85 mL 37.7 mL
1 mM 1.89 mL 9.43 mL 18.85 mL
5 mM 0.38 mL 1.89 mL 3.77 mL

*The above data is based on the productmolecular weight 530.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13029
Actions Inhibitor
CAS No. 926037-48-1
Formula C27H21F3N8O
M. Wt 530.5
Solubility DMSO
Purity >98%
Synonyms IY-5511
SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=NC=CN=C5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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