(rel)-Tivantinib

Catalog No.: A34315
c-MET Inhibitor
(rel)-Tivantinib is a potent and selective inhibitor of the receptor tyrosine kinase c-MET. This compound also targets GSK3α and GSK3β, which are involved in the cellular mechanisms associated with non-small cell lung cancer (NSCLC). Its inhibition of c-MET signaling pathways and modulation of GSK3 activity position (rel)-Tivantinib as a valuable tool for researching therapeutic strategies in cancer biology.
Grouped product items
Size Price Stock Qty
25mg
$120.00
In stock
50mg
$180.00
In stock
100mg
$270.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(rel)-Tivantinib is a potent and selective inhibitor of the receptor tyrosine kinase c-MET. This compound also targets GSK3α and GSK3β, which are involved in the cellular mechanisms associated with non-small cell lung cancer (NSCLC). Its inhibition of c-MET signaling pathways and modulation of GSK3 activity position (rel)-Tivantinib as a valuable tool for researching therapeutic strategies in cancer biology.
Product Information
Catalog NumA34315
FormulaC23H19N3O2
Molecular Weight369.42
CAS Number905853-99-8
SMILESO=C(NC1=O)[C@@H](C2=CN3C4=C(C=CC=C42)CCC3)[C@@H]1C5=CNC6=C5C=CC=C6
Synonyms(rel)-ARQ 197; (rel)-(3R,4R)-ARQ 198
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