Catalog No.: A12535
BTK inhibitor
RN486 is a Bruton's tyrosine kinase (Btk) inhibitor.
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Biological Activity
Discription RN486 is a Bruton's tyrosine kinase (Btk) inhibitor.
Target Value
Product Information
Catalog Num A12535
Formula C35H35FN6O3
Molecular Weight 606.7
CAS Number 1242156-23-5
Synonyms RN-486,RN 486

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO Warmed: 61 mg/mL (100.54 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+30% PEG 300+10% Tween 80+ddH2O 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.48 mL 82.41 mL 164.83 mL
0.5 mM 3.3 mL 16.48 mL 32.97 mL
1 mM 1.65 mL 8.24 mL 16.48 mL
5 mM 0.33 mL 1.65 mL 3.3 mL
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Calculate the dilution required to prepare a stock solution.
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