RO9021

Catalog No.: A16686
ATP-competitive SYK inhibitor
RO9021 is an orally bioavailable, novel ATP-competitive inhibitor of SYK, with an average IC50 of 5.6 nM.
Grouped product items
Product Name Price Stock Qty
RO9021 1mg
$90.00
In stock
RO9021 5mg
$270.00
In stock
RO9021 10mg
$460.00
In stock
RO9021 50mg
$1,380.00
In stock
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Biological Activity
Discription RO9021 is an orally bioavailable, novel ATP-competitive inhibitor of SYK, with an average IC50 of 5.6 nM.
Product Information
Catalog Num A16686
Formula C18H25N7O
Molecular Weight 355.44
CAS Number 1446790-62-0
SMILES NC(C1=C(NC2=CC=C(C)C(C)=N2)C=C(N[C@H]3[C@@H](N)CCCC3)N=N1)=O
Synonyms RO 9021, RO-9021
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 5 mg/mL (14.06 mM)
Water Insoluble
Ethanol 7 mg/mL (19.69 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.13 mL 140.67 mL 281.34 mL
0.5 mM 5.63 mL 28.13 mL 56.27 mL
1 mM 2.81 mL 14.07 mL 28.13 mL
5 mM 0.56 mL 2.81 mL 5.63 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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