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Catalog No.: A16686

ATP-competitive SYK inhibitor


RO9021 Chemical Structure

CAS NO. 1446790-62-0

RO9021 is an orally bioavailable, novel ATP-competitive inhibitor of SYK, with an average IC50 of 5.6 nM.

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Biological Activity

RO9021 is an orally bioavailable, novel ATP-competitive inhibitor of SYK, with an average IC50 of 5.6 nM.
In vitro DMSO 5 mg/mL (14.06 mM)
Water Insoluble
Ethanol 7 mg/mL (19.69 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.13 mL 140.67 mL 281.34 mL
0.5 mM 5.63 mL 28.13 mL 56.27 mL
1 mM 2.81 mL 14.07 mL 28.13 mL
5 mM 0.56 mL 2.81 mL 5.63 mL

*The above data is based on the productmolecular weight 355.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16686
Actions Inhibitor
CAS No. 1446790-62-0
Formula C18H25N7O
M. Wt 355.44
Purity >98%
Synonyms RO 9021, RO-9021

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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