Signaling Pathway
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| Discription | S55746 (BLC201) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 (BLC201) has antitumor activity with low toxicity. | ||
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| Catalog Num | A18361 |
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| Formula | C43H42N4O6 |
| Molecular Weight | 710.82 |
| CAS Number | 1448584-12-0 |
| SMILES | O=C(C1=C2CCCCN2C(C3=C(C(N4CC5=C(C=CC=C5)C[C@H]4CN6CCOCC6)=O)C=C(OCO7)C7=C3)=C1)N(C8=CC=C(O)C=C8)C9=CC=CC=C9 |
| Synonyms | BLC201 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 88 mg/mL (123.8 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.07 mL | 70.34 mL | 140.68 mL |
| 0.5 mM | 2.81 mL | 14.07 mL | 28.14 mL |
| 1 mM | 1.41 mL | 7.03 mL | 14.07 mL |
| 5 mM | 0.28 mL | 1.41 mL | 2.81 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
