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S55746 (BLC201) is a potent, orally active and selective BCL-2 inhibitor, with a Ki of 1.3 nM and a Kd of 3.9 nM. S55746 (BLC201) has antitumor activity with low toxicity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.07 mL | 70.34 mL | 140.68 mL |
| 0.5 mM | 2.81 mL | 14.07 mL | 28.14 mL |
| 1 mM | 1.41 mL | 7.03 mL | 14.07 mL |
| 5 mM | 0.28 mL | 1.41 mL | 2.81 mL |
*The above data is based on the productmolecular weight 710.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18361 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 710.82 |
| Formula | C43H42N4O6 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1448584-12-0 |
| Synonyms | BLC201 |
| SMILES | O=C(C1=C2CCCCN2C(C3=C(C(N4CC5=C(C=CC=C5)C[[email protected]]4CN6CCOCC6)=O)C=C(OCO7)C7=C3)=C1)N(C8=CC=C(O)C=C8)C9=CC=CC=C9 |
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