S63845

Catalog No.: A18356
myeloid cell leukemia 1 (MCL1) inhibitor
S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1.
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Product Name Stock
S63845 1mg
S63845 5mg
S63845 10mg
S63845 50mg
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Biological Activity
Discription S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1.
Targets
Target Value
Product Information
Catalog Num A18356
Formula C39H37ClF4N6O6S
Molecular Weight 829.26
CAS Number 1799633-27-4
SMILES CC(C(Cl)=C(OCCN1CCN(C)CC1)C=C2)=[C@@]2[C@]3=C(C4=CC=C(F)O4)SC5=NC=NC(O[C@H](CC6=C(OCC7=CC=NN7CC(F)(F)F)C=CC=C6)C(O)=O)=C53
Synonyms S-63845, S 63845
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 91 mg/mL (109.73 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.06 mL 60.29 mL 120.59 mL
0.5 mM 2.41 mL 12.06 mL 24.12 mL
1 mM 1.21 mL 6.03 mL 12.06 mL
5 mM 0.24 mL 1.21 mL 2.41 mL
Useful Calculator

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This equation is commonly abbreviated as: C1V1 = C2V2

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