Sabutoclax

Catalog No.: A12823
Bcl-2 inhibitor
Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
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Product Name Price Stock Qty
Sabutoclax 5mg
$145.00
In stock
Sabutoclax 10mg
$250.00
In stock
Sabutoclax 25mg
$320.00
In stock
Sabutoclax 50mg
$675.00
In stock
Sabutoclax 10mM * 1mL in DMSO
$409.00
In stock
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Adooq Products cited in reputable paper
Adooq's Sabutoclax has been cited by 1 publications
  • Christopher D. Graham, .et al. , Oncotarget, 2017, Jan 31; 8(5): 8670-8678 PMID: 28055968
  • Biological Activity
    Discription Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
    Targets
    Target Value
    Product Information
    Catalog Num A12823
    Formula C42H40N2O8
    Molecular Weight 700.78
    CAS Number 1228108-65-3
    SMILES CC1=C(C(=C2C=C(C(=C(C2=C1)C(=O)NC[C@H](C)C3=CC=CC=C3)O)O)O)C4=C(C=C5C(=C4O)C=C(C(=C5C(=O)NC[C@H](C)C6=CC=CC=C6)O)O)C
    Synonyms BI-97C1,BI97C1
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO Warmed: 93 mg/mL (132.7 mM)
    Water Insoluble
    Ethanol Warmed: 50 mg/mL (71.34 mM)
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 14.27 mL 71.35 mL 142.7 mL
    0.5 mM 2.85 mL 14.27 mL 28.54 mL
    1 mM 1.43 mL 7.13 mL 14.27 mL
    5 mM 0.29 mL 1.43 mL 2.85 mL
    Useful Calculator

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    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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