Sacibertinib is a selective tyrosine kinase inhibitor targeting Trk receptors, demonstrating an EC50 of 110 nM for EGFR-TK phosphorylation and 244 nM for HER2. It exhibits pronounced antineoplastic activity, making it a valuable tool in cancer research. Sacibertinib is suitable for studies focused on kinase signaling pathways and potential therapeutic interventions in tumors associated with Trk activation.
Sacibertinib is a selective tyrosine kinase inhibitor targeting Trk receptors, demonstrating an EC50 of 110 nM for EGFR-TK phosphorylation and 244 nM for HER2. It exhibits pronounced antineoplastic activity, making it a valuable tool in cancer research. Sacibertinib is suitable for studies focused on kinase signaling pathways and potential therapeutic interventions in tumors associated with Trk activation.
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