Signaling Pathway
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| Discription | Selonsertib is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. | ||
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| Targets |
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| Catalog Num | A15991 |
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| Formula | C24H24FN7O |
| Molecular Weight | 445.5 |
| CAS Number | 1448428-04-3 |
| SMILES | O=C(NC1=NC(C2=NN=CN2C(C)C)=CC=C1)C3=CC(N4C=C(C5CC5)N=C4)=C(C)C=C3F |
| Synonyms | GS-4997, GS4997, GS 4997 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 34 mg/mL (76.31 mM) | |
| Water | Insoluble | ||
| Ethanol | 23 mg/mL (51.63 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.45 mL | 112.23 mL | 224.47 mL |
| 0.5 mM | 4.49 mL | 22.45 mL | 44.89 mL |
| 1 mM | 2.24 mL | 11.22 mL | 22.45 mL |
| 5 mM | 0.45 mL | 2.24 mL | 4.49 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
