SGI-7079

Catalog No.: A15864

Axl inhibitor

SGI-7079 Chemical Structure

CAS NO. 1239875-86-5

SGI-7079 ,a novel selective Axl inhibitor, inhibits tumor growth in a dose dependent manner and is a potential therapeutic target for overcoming EGFR inhibitor resistance.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
25 mg
$280.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SGI-7079 ,a novel selective Axl inhibitor, inhibits tumor growth in a dose dependent manner and is a potential therapeutic target for overcoming EGFR inhibitor resistance.
Targets
Target Value
Met
Mer
YES
RET
FLT3
AxlIC50: 58nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.95 mL 109.76 mL 219.52 mL
0.5 mM 4.39 mL 21.95 mL 43.9 mL
1 mM 2.2 mL 10.98 mL 21.95 mL
5 mM 0.44 mL 2.2 mL 4.39 mL

*The above data is based on the productmolecular weight 455.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15864
Actions Inhibitor
M. Wt 455.53
Formula C26H26FN7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1239875-86-5
Synonyms SGI7079, SGI 7079
SMILES N#CCC1=CC=CC(C2=C3C(NC=C3C)=NC(NC4=CC=C(N5CCN(C)CC5)C(F)=C4)=N2)=C1

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