Sitravatinib (MGCD516)

Catalog No.: A16259

RTK inhibitor

Sitravatinib (MGCD516)

Sitravatinib (MGCD516) Chemical Structure

CAS NO. 1123837-84-2

Sitravatinib is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$110.00
50 mg
$280.00
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Biological Activity

Sitravatinib is a novel small molecule inhibitor targeting multiple RTKs involved in driving sarcoma cell growth.
In vitro DMSO 98 mg/mL (155.63 mM)
Water Insoluble
Ethanol 98 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.88 mL 79.41 mL 158.81 mL
0.5 mM 3.18 mL 15.88 mL 31.76 mL
1 mM 1.59 mL 7.94 mL 15.88 mL
5 mM 0.32 mL 1.59 mL 3.18 mL

*The above data is based on the productmolecular weight 629.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16259
Actions Inhibitor
CAS No. 1123837-84-2
Formula C33H29F2N5O4S
M. Wt 629.68
Purity >98%
Synonyms MGCD516, MG516
SMILES O=C(C1(C(NC2=CC=C(F)C=C2)=O)CC1)NC3=CC=C(OC4=C5C(C=C(C6=NC=C(CNCCOC)C=C6)S5)=NC=C4)C(F)=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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