SM-164

Name: SM-164
Brand: Adooq Bioscience
SKU: A15800
Rating: 100 (1 reviews)

Catalog No.: A15800

cIAP-2 antagonist

Product Citations (1)

SM-164 Chemical Structure

CAS NO. 957135-43-2

SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.

Availability: In stock

Package	Price	Qty
5 mg	$280.00
10 mg	$500.00
25 mg	$1,000.00
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Publications Citing Use of Adooq SM-164

Caroline Moerke, .et al. The anticonvulsive Phenhydan® suppresses extrinsic cell death, Cell Death Differ, 2018, Nov 15 PMID: 30442947

Biological Activity

Solubility *

In vitro	DMSO	3 mg/mL (2.67 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.92 mL	44.59 mL	89.17 mL
0.5 mM	1.78 mL	8.92 mL	17.83 mL
1 mM	0.89 mL	4.46 mL	8.92 mL
5 mM	0.18 mL	0.89 mL	1.78 mL

*The above data is based on the productmolecular weight 1121.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A15800
Actions	Antagonist
CAS No.	957135-43-2
Formula	C62H84N14O6
M. Wt	1121.42
Purity	>98%
Synonyms	SM 164, SM164
SMILES	CC(C(=O)NC1CCCCC2CCC(N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)C(C7=CC=CC=C7)NC(=O)C8CCC9N8C(=O)C(CCCC9)NC(=O)C(C)NC)NC
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.