SM-164

Catalog No.: A15800

cIAP-2 antagonist

SM-164

SM-164 Chemical Structure

CAS NO. 957135-43-2

SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.

Availability: In stock

Package Price Qty
5 mg
$280.00
10 mg
$500.00
25 mg
$1,000.00
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  • Caroline Moerke, .et al. The anticonvulsive Phenhydan® suppresses extrinsic cell death, Cell Death Differ, 2018, Nov 15 PMID: 30442947

Biological Activity

SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 8.92 mL 44.59 mL 89.17 mL
0.5 mM 1.78 mL 8.92 mL 17.83 mL
1 mM 0.89 mL 4.46 mL 8.92 mL
5 mM 0.18 mL 0.89 mL 1.78 mL

*The above data is based on the productmolecular weight 1121.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15800
Actions Antagonist
M. Wt 1121.42
Formula C62H84N14O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 957135-43-2
Synonyms SM 164, SM164
SMILES CC(C(=O)NC1CCCCC2CCC(N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)C(C7=CC=CC=C7)NC(=O)C8CCC9N8C(=O)C(CCCC9)NC(=O)C(C)NC)NC

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