SM-164

Catalog No.: A15800
cIAP-2 antagonist
SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.
Grouped product items
Size Price Stock Qty
1mg
$110.00
In stock
2mg
$165.00
In stock
5mg
$275.00
In stock
10mg
$435.00
In stock
25mg
$710.00
In stock
50mg
$990.00
In stock
100mg
$1,780.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's SM-164 has been cited by 3 publications
  • Antonella Antignani, .et al. , FASEB J, 2023, Dec;37(12):e23292 PMID: 37971407
  • Hanna Yuk, .et al. , Antioxidants (Basel), 2021, Aug 25;10(9):1347 PMID: 34572979
  • Caroline Moerke, .et al. , Cell Death Differ, 2018, Nov 15 PMID: 30442947
  • Biological Activity
    Discription SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A15800
    Formula C62H84N14O6
    Molecular Weight 1121.42
    CAS Number 957135-43-2
    SMILES CC(C(=O)NC1CCCCC2CCC(N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)C(C7=CC=CC=C7)NC(=O)C8CCC9N8C(=O)C(CCCC9)NC(=O)C(C)NC)NC
    Synonyms SM 164, SM164
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 3 mg/mL (2.67 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 8.92 mL 44.59 mL 89.17 mL
    0.5 mM 1.78 mL 8.92 mL 17.83 mL
    1 mM 0.89 mL 4.46 mL 8.92 mL
    5 mM 0.18 mL 0.89 mL 1.78 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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