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Publications citing Adooq Products
SM-164 Citations (1)
- Caroline Moerke,et al. The anticonvulsive Phenhydan? suppresses extrinsic cell death, Cell Death Differ, 2018, Nov 15 30442947
Chemical Information
| Catalog Num | A15800 |
|---|---|
| Actions | Antagonist |
| M. Wt | 1121.42 |
| Formula | C62H84N14O6 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 957135-43-2 |
| Synonyms | SM 164, SM164 |
| SMILES code | CC(C(=O)NC1CCCCC2CCC(N2C1=O)C(=O)NC(C3=CC=CC=C3)C4=CN(N=N4)CCCCC5=CC=C(C=C5)CCCCN6C=C(N=N6)C(C7=CC=CC=C7)NC(=O)C8CCC9N8C(=O)C(CCCC9)NC(=O)C(C)NC)NC |
| Chemical Name | (3S,6R,10aR)-6-((S)-2-(methylamino)propanamido)-N-((R)-(1-(4-(4-(4-(4-((S)-((3S,6S,10aS)-6-((S)-2-(methylamino)propanamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamido)(phenyl)methyl)-1H-1,2,3-triazol-1-yl)butyl)phenyl)butyl)-1H-1,2,3-triazol-4-yl)( |
Description |
SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP protein with a Ki value of 0.56 nM, and binds to cIAP-1 and cIAP-2 proteins with Ki values of 0.31 and 1.1 nM, respectively. | |||||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 8.92 mL | 44.59 mL | 89.17mL |
| 0.5 mM | 1.78 mL | 8.92 mL | 17.83 mL |
| 1 mM | 0.89 mL | 4.46 mL | 8.92 mL |
| 5 mM | 0.18 mL | 0.89 mL | 1.78 mL |
*The above data is based on the productmolecular weight 1121.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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