SN38-COOH is a key component for the synthesis of antibody-drug conjugates (ADCs). It serves as a functionalized form of SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, which effectively inhibits DNA and RNA synthesis in target cells. This compound is utilized in research focused on targeted cancer therapies, allowing for the precise delivery of cytotoxic agents to improve therapeutic efficacy while minimizing systemic toxicity.
SN38-COOH is a key component for the synthesis of antibody-drug conjugates (ADCs). It serves as a functionalized form of SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, which effectively inhibits DNA and RNA synthesis in target cells. This compound is utilized in research focused on targeted cancer therapies, allowing for the precise delivery of cytotoxic agents to improve therapeutic efficacy while minimizing systemic toxicity.
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