SPDB-DM4

Catalog No.: A21413

SPDB-DM4

SPDB-DM4 Chemical Structure

CAS NO. 1626359-62-3

SPDB-DM4 is a drug-linker conjugate for ADC by using the maytansinebased payload (DM4, a tubulin inhibitor) via a SPDB linker, exhibiting potent anti-tumor activity.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $378.00

Special Price $302.40

5 mg

Regular Price: $1,134.00

Special Price $907.20

10 mg

Regular Price: $1,932.00

Special Price $1,545.60

50 mg

Regular Price: $5,796.00

Special Price $4,636.80

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Biological Activity

SPDB-DM4 is a drug-linker conjugate for ADC by using the maytansinebased payload (DM4, a tubulin inhibitor) via a SPDB linker, exhibiting potent anti-tumor activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 10.04 mL 50.22 mL 100.44 mL
0.5 mM 2.01 mL 10.04 mL 20.09 mL
1 mM 1 mL 5.02 mL 10.04 mL
5 mM 0.2 mL 1 mL 2.01 mL

*The above data is based on the productmolecular weight 995.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21413
CAS No. 1626359-62-3
Formula C46H63ClN4O14S2
M. Wt 995.59
Purity >98%
SMILES C[[email protected]]1([[email protected]](CC(N(C(C=C2C=C3OC)=C3Cl)C)=O)OC([[email protected]](C)N(C)C(CCC(C)(C)SSCCCC(ON(C4=O)C(CC4)=O)=O)=O)=O)[[email protected]]([[email protected]@H]([[email protected]](OC5=O)([H])C[[email protected]]([[email protected]](/C=C/C=C(C)/C2)([H])OC)(N5)O)C)O1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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