Spevatamig

Catalog No.: AT0762

Spevatamig is a bispecific antibody of the (H-γ1_L-κ)_(H-γ1_L-κ) type, designed to target CD47 and CLDN18. This dual specificity facilitates its application in the selective targeting and inhibition of pathways crucial in cancer cell survival and immune evasion, making it a valuable tool for research in oncology and immunotherapy.

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Grouped product items
Size	Price	Stock
1mg	$450.00	In stock
5mg	$1,400.00	In stock
10mg	$2,400.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	Spevatamig is a bispecific antibody of the (H-γ1_L-κ)_(H-γ1_L-κ) type, designed to target CD47 and CLDN18. This dual specificity facilitates its application in the selective targeting and inhibition of pathways crucial in cancer cell survival and immune evasion, making it a valuable tool for research in oncology and immunotherapy.
Targets	CD47/CLDN18

Product Information

Catalog Num	AT0762
CAS Number	2928515-36-8
Isotype	(H-gamma1_L-kappa)_(H-gamma1_L-kappa)

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What are Biosimilar Antibodies?

Biosimilar antibodies are research-grade recombinant antibodies designed to closely resemble approved therapeutic antibodies in terms of amino acid sequence, structural characteristics, and biological activity. These antibodies are generated using recombinant expression technologies and retain the same variable regions as their corresponding reference therapeutics, thereby preserving target specificity and binding affinity. Owing to these properties, biosimilar antibodies serve as reliable and cost-effective research reagents for applications in drug discovery, pharmacological studies, and basic biomedical research. Research-grade biosimilar antibodies have been successfully expressed and functionally validated against a wide range of widely studied targets. These antibodies can be directly utilized as positive control reagents in drug discovery programs, as well as reference tools for rapid verification of the biological functions of target proteins in biochemical and cellular assays.