SRI 31215 TFA

Catalog No.: A21775

triplex matriptase inhibitor

SRI 31215 TFA

SRI 31215 TFA Chemical Structure

CAS NO. 1832686-44-8

SRI 31215 (TFA), a triplex inhibitor of matriptase, hepsin and hepatocyte growth factor activator (HGFA) with IC50s of 0.69 μM, 0.65 μM, 0.3 μM, blocks pro-HGF activation and thus mimics the activity of HAI-1/2.

Availability: In stock

Package Price Qty
5 mg
$162.00
10 mg
$279.00
50 mg
$828.00
100 mg
$1,656.00
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Biological Activity

SRI 31215 (TFA), a triplex inhibitor of matriptase, hepsin and hepatocyte growth factor activator (HGFA) with IC50s of 0.69 μM, 0.65 μM, 0.3 μM, blocks pro-HGF activation and thus mimics the activity of HAI-1/2.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.74 mL 93.7 mL 187.41 mL
0.5 mM 3.75 mL 18.74 mL 37.48 mL
1 mM 1.87 mL 9.37 mL 18.74 mL
5 mM 0.37 mL 1.87 mL 3.75 mL

*The above data is based on the productmolecular weight 533.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21775
Actions Inhibitor
CAS No. 1832686-44-8
Formula C27H34F3N5O3
M. Wt 533.59
Purity >98%
Synonyms SRI-31215, SRI31215
SMILES N=C(C1=CC=CC(N2CC(C)CN(CC3CCN(CC4=CC=CC=C4)CC3)C2=O)=C1)N.OC(C(F)(F)F)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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