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STING agonist-49-PAB-Ala-Val-CO-C2-mal

Catalog No.: A41587
Drug-Linker Conjugate for ADC
STING agonist-49-PAB-Ala-Val-CO-C2-mal is a drug-linker conjugate designed for antibody-drug conjugate (ADC) synthesis. This compound functions as a pep-cSTING linker-payload, promoting the activation of the STING pathway to enhance therapeutic efficacy. Its applications include facilitating targeted delivery of cytotoxic agents to enhance anti-tumor immunity and investigating the role of STING in immune modulation. This versatile agent is instrumental for research in targeted therapeutics and immune-related studies.
STING agonist-49-PAB-Ala-Val-CO-C2-mal 2803608-03-7 Drug-Linker Conjugate for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSTING agonist-49-PAB-Ala-Val-CO-C2-mal is a drug-linker conjugate designed for antibody-drug conjugate (ADC) synthesis. This compound functions as a pep-cSTING linker-payload, promoting the activation of the STING pathway to enhance therapeutic efficacy. Its applications include facilitating targeted delivery of cytotoxic agents to enhance anti-tumor immunity and investigating the role of STING in immune modulation. This versatile agent is instrumental for research in targeted therapeutics and immune-related studies.
Product Information
Catalog NumA41587
FormulaC62H73N17O13
Molecular Weight1264.35
CAS Number2803608-03-7
SMILESO=C([C@H](C)NC([C@H](C(C)C)NC(CCN1C(C=CC1=O)=O)=O)=O)NC2=CC=C(COC(N(C)CCCOC3=CC(C(N)=O)=CC4=C3N(C(NC(C5=CC(C)=NN5CC)=O)=N4)C/C=C/CN6C(NC(C7=CC(C)=NN7CC)=O)=NC8=CC(C(N)=O)=CC(OC)=C86)=O)C=C2
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC