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$0.00 - Yin Kang, .et al. Sulforaphane Prevents Right Ventricular Injury and Reduces Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension, Am J Physiol Heart Circ Physiol, 2020, Apr 1;318(4):H853-H866 PMID: 32108526
- Avner Adini, .et al. PR1P Stabilizes VEGF and Upregulates its Signaling to Reduce Elastase Induced Murine Emphysema, Am J Respir Cell Mol Biol, 2020, Jul 14 PMID: 32663413
Biological Activity
SU 5416 is an inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and RET.
| In vitro (25°C) | DMSO | 19 mg/mL (79.73 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (8.39 mM) | ||
| In vivo | 5% DMSO+40%PEG 300+ 5% Tween80 + ddH2O | 0.4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 41.97 mL | 209.84 mL | 419.67 mL |
| 0.5 mM | 8.39 mL | 41.97 mL | 83.93 mL |
| 1 mM | 4.2 mL | 20.98 mL | 41.97 mL |
| 5 mM | 0.84 mL | 4.2 mL | 8.39 mL |
*The above data is based on the productmolecular weight 238.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12437 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 204005-46-9 |
| Formula | C15H14N2O |
| M. Wt | 238.28 |
| Purity | >98% |
| Synonyms | SU-5416, SU5416 |
| SMILES | CC1=CC(=C(N1)/C=C\2/C3=CC=CC=C3NC2=O)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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