Total item
Cart Subtotal
$0.00 - Michel R. Corboz, .et al. Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension, Eur J Pharmacol, 2022, 916: 174484 PMID: 34508752
- Avner Adini, .et al. PR1P Stabilizes VEGF and Upregulates its Signaling to Reduce Elastase Induced Murine Emphysema, Am J Respir Cell Mol Biol, 2020, Jul 14 PMID: 32663413
- Yin Kang, .et al. Sulforaphane Prevents Right Ventricular Injury and Reduces Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension, Am J Physiol Heart Circ Physiol, 2020, Apr 1;318(4):H853-H866 PMID: 32108526
Biological Activity
SU 5416 is an inhibitor of vascular endothelial growth factor receptor (VEGFR) that also inhibits other tyrosine kinases KIT, MET, FLT3 and RET.
| In vitro (25°C) | DMSO | 19 mg/mL (79.73 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (8.39 mM) | ||
| In vivo | 5% DMSO+40%PEG 300+ 5% Tween80 + ddH2O | 0.4 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 41.97 mL | 209.84 mL | 419.67 mL |
| 0.5 mM | 8.39 mL | 41.97 mL | 83.93 mL |
| 1 mM | 4.2 mL | 20.98 mL | 41.97 mL |
| 5 mM | 0.84 mL | 4.2 mL | 8.39 mL |
*The above data is based on the productmolecular weight 238.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12437 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 204005-46-9 |
| Formula | C15H14N2O |
| M. Wt | 238.28 |
| Purity | >98% |
| Synonyms | SU-5416, SU5416 |
| SMILES | CC1=CC(=C(N1)/C=C\2/C3=CC=CC=C3NC2=O)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Axitinib
Axitinib is a small molecule tyrosine kinase inhibitor,which inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derive…
Motesanib Diphosphate (AMG-706)
Motesanib, also known as AMG-706, is an orally administered multikinase inhibitor that selectively targets VEGF receptors, platelet-derived …
SKLB1002
SKLB1002 is a new potent VEGFR2 inhibitor, which could significantly inhibit HUVEC proliferation, migration, invasion, and tube formation.
Brivanib alaninate (BMS-582664)
Brivanib alaninate (BMS-582664) is a dual tyrosine kinase inhibitor of VEGFR and FGFR signaling.
ZM 323881 hydrochloride
ZM 323881 is a potent and selective inhibitor of the kinase activity of the human vascular endothelial growth factor receptor 2 (VEGFR2/KDR)…
NVP-BAW2881
NVP-BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity …
Telatinib (BAY 57-9352)
Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3…
Toceranib (PHA 291639, SU 11654)
Toceranib is a kinase inhibitor with both antitumor and antiangiogenic activity through inhibition of KIT, vascular endothelial growth facto…
Keywords:buy SU 5416 (Semaxinib) | SU 5416 (Semaxinib) Supplier | purchase | cost | manufacturer | order | distributor | buy 204005-46-9| 204005-46-9 Supplier | purchase 204005-46-9 | 204005-46-9 cost | 204005-46-9 manufacturer | order 204005-46-9 | 204005-46-9 distributor
Adooq Quality Guarantee
We promise all products perform as described.