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Biological Activity
SU1498 is a selective inhibitor of the VEGFR2; inhibits Flk-1 with an IC50 of value of 700 nM.
| In vitro | DMSO | 69 mg/mL (176.68 mM) | |
| Water | Insoluble | ||
| Ethanol | 69 mg/mL (176.68 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.61 mL | 128.03 mL | 256.07 mL |
| 0.5 mM | 5.12 mL | 25.61 mL | 51.21 mL |
| 1 mM | 2.56 mL | 12.8 mL | 25.61 mL |
| 5 mM | 0.51 mL | 2.56 mL | 5.12 mL |
*The above data is based on the productmolecular weight 390.52. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12472 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 168835-82-3 |
| Formula | C25H30N2O2 |
| M. Wt | 390.52 |
| Purity | >98% |
| Synonyms | AG 1498, AG-1498, AG1498; Tyrphostin SU 1498, SU-1498 |
| SMILES | O=C(NCCCC1=CC=CC=C1)/C(C#N)=C/C2=CC(C(C)C)=C(O)C(C(C)C)=C2 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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