Syk-IN-1

Catalog No.: A84731
Syk Inhibitor
Syk-IN-1 is a highly potent inhibitor of Syk (spleen tyrosine kinase), demonstrating an IC50 value of 35 nM. This compound effectively disrupts Syk-mediated signaling pathways, making it valuable for studies involving immune response, cell proliferation, and apoptosis. Syk-IN-1 is suitable for research applications focused on hematological malignancies and inflammatory diseases, facilitating the exploration of Syk's role in various biological processes.
Grouped product items
Size Price Stock Qty
5mg
$410.00
In stock
10mg
$715.00
In stock
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionSyk-IN-1 is a highly potent inhibitor of Syk (spleen tyrosine kinase), demonstrating an IC50 value of 35 nM. This compound effectively disrupts Syk-mediated signaling pathways, making it valuable for studies involving immune response, cell proliferation, and apoptosis. Syk-IN-1 is suitable for research applications focused on hematological malignancies and inflammatory diseases, facilitating the exploration of Syk's role in various biological processes.
Product Information
Catalog NumA84731
FormulaC18H22N8O
Molecular Weight366.42
CAS Number1491150-77-6
SMILESNC(C1=NN=C(N[C@@H]2CCCC[C@@H]2N)N=C1NC3=CC=CC4=C3NC=C4)=O
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