Syk Inhibitor II dihydrochloride dihydrate is a selective and ATP-competitive inhibitor of Syk with an IC50 of 41 nM. This compound effectively inhibits 5-HT release from RBL cells, demonstrating an IC50 of 460 nM. With reduced potency against other kinases, it holds potential for applications in treating allergic responses and exploring the role of Syk in various immunological processes.
Syk Inhibitor II dihydrochloride dihydrate is a selective and ATP-competitive inhibitor of Syk with an IC50 of 41 nM. This compound effectively inhibits 5-HT release from RBL cells, demonstrating an IC50 of 460 nM. With reduced potency against other kinases, it holds potential for applications in treating allergic responses and exploring the role of Syk in various immunological processes.
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