Tafamidis meglumine

Catalog No.: A18045

transthyretin (TTR) stabilizer

Tafamidis meglumine

Tafamidis meglumine Chemical Structure

CAS NO. 951395-08-7

Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $54.00

Special Price $43.20

10 mg

Regular Price: $93.00

Special Price $74.40

50 mg

Regular Price: $276.00

Special Price $220.80

100 mg

Regular Price: $552.00

Special Price $441.60

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Biological Activity

Tafamidis meglumine (Fx-1006A) is a potent and selective transthyretin (TTR) stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.87 mL 99.34 mL 198.68 mL
0.5 mM 3.97 mL 19.87 mL 39.74 mL
1 mM 1.99 mL 9.93 mL 19.87 mL
5 mM 0.4 mL 1.99 mL 3.97 mL

*The above data is based on the productmolecular weight 503.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18045
Actions Stabilizer
CAS No. 951395-08-7
Formula C21H24Cl2N2O8
M. Wt 503.33
Purity >98%
Synonyms Fx-1006A, Fx1006A, Fx 1006A
SMILES O=C(C1=CC=C2N=C(C3=CC(Cl)=CC(Cl)=C3)OC2=C1)O.O[[email protected]@H]([[email protected]@H]([[email protected]@H](CO)O)O)[[email protected]@H](O)CNC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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