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TAK 259

α1D Adrenoceptor Antagonist

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Catalog No. A16186

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TAK 259 10mg A16186-10
$90.00
TAK 259 25mg A16186-25
$180.00
TAK 259 100mg A16186-100
$540.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TAK-259 is a Novel, Selective, and Orally Active α1D Adrenoceptor Antagonist (α1D, Ki = 1.1 nM) with Anti-urinary Frequency Effects and Reducing Human Ether-a-go-go-Related Gene (hERG) Liabilities.

TAK 259

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Chemical Information

Catalog Num A16186
Actions Antagonist
M. Wt 410.7
Formula C14H14Cl3N3O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1192347-42-4
Synonyms TAK259, TAK-259
SMILES O=C(C1=CC(Cl)=CN(CC2=CC(Cl)=CC=C2S(=O)(C)=O)C1=N)N.[H]Cl

Biological Activity

Description
TAK-259 is a Novel, Selective, and Orally Active α1D Adrenoceptor Antagonist (α1D, Ki = 1.1 nM) with Anti-urinary Frequency Effects and Reducing Human Ether-a-go-go-Related Gene (hERG) Liabilities.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.35 mL 121.74 mL 243.49mL
0.5 mM 4.87 mL 24.35 mL 48.7 mL
1 mM 2.43 mL 12.17 mL 24.35 mL
5 mM 0.49 mL 2.43 mL 4.87 mL

*The above data is based on the productmolecular weight 410.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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