TAS05567 is a highly selective, ATP-competitive inhibitor of Syk, exhibiting an IC50 of 0.37 nM. This compound demonstrates potent inhibition of Syk alongside four other kinases (FLT3, JAK2, KDR, and RET) at IC50 values of 10 nM, 4.8 nM, 600 nM, and 29 nM, respectively. TAS05567 is suitable for research applications related to humoral immune-mediated inflammatory conditions, including various autoimmune and allergic diseases.
TAS05567 is a highly selective, ATP-competitive inhibitor of Syk, exhibiting an IC50 of 0.37 nM. This compound demonstrates potent inhibition of Syk alongside four other kinases (FLT3, JAK2, KDR, and RET) at IC50 values of 10 nM, 4.8 nM, 600 nM, and 29 nM, respectively. TAS05567 is suitable for research applications related to humoral immune-mediated inflammatory conditions, including various autoimmune and allergic diseases.
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