TCB-32 hydrochloride

Catalog No.: A33498
FGFR1 Agonist
TCB-32 hydrochloride is an FGFR1 agonist with an EC50 of 0.88 μM. This compound effectively enhances cell proliferation by activating the FGFR1 signaling pathway, notably promoting downstream ERK 1/2 activity. With excellent thermal stability, TCB-32 hydrochloride serves as a viable replacement for bFGF in serum-free cell culture media. Its applications extend to tissue repair and the study of wound healing in diseases such as psoriasis and eczema.
Grouped product items
Size Price Stock Qty
1mg
$335.00
In stock
5mg
$860.00
In stock
10mg
$1,430.00
In stock
25mg
$2,855.00
In stock
50mg
$4,430.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Biological Activity
DescriptionTCB-32 hydrochloride is an FGFR1 agonist with an EC50 of 0.88 μM. This compound effectively enhances cell proliferation by activating the FGFR1 signaling pathway, notably promoting downstream ERK 1/2 activity. With excellent thermal stability, TCB-32 hydrochloride serves as a viable replacement for bFGF in serum-free cell culture media. Its applications extend to tissue repair and the study of wound healing in diseases such as psoriasis and eczema.
Product Information
Catalog NumA33498
FormulaC32H44Cl4N18O2
Molecular Weight854.62
CAS Number169764-95-8
SMILESO=C(C1=CC=CC(C(NC2=CC(/C(C)=N/NC(N)=N)=CC(/C(C)=N/NC(N)=N)=C2)=O)=C1)NC3=CC(/C(C)=N/NC(N)=N)=CC(/C(C)=N/NC(N)=N)=C3.Cl.Cl.Cl.Cl
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