TCS 359

Catalog No.: A12427

FLT3 inhibitor

TCS 359

TCS 359 Chemical Structure

CAS NO. 301305-73-7

TCS 359 is a potent inhibitor of FLT3 receptor tyrosine kinase (IC50 = 42 nM) that displays selectivity over a range of other kinases.

Availability: In stock

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10 mg

Regular Price: $85.00

Special Price $68.00

25 mg

Regular Price: $170.00

Special Price $136.00

50 mg

Regular Price: $295.00

Special Price $236.00

100 mg

Regular Price: $550.00

Special Price $440.00

10mM * 1mL in DMSO

Regular Price: $90.00

Special Price $72.00

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Biological Activity

TCS 359 is a potent inhibitor of FLT3 receptor tyrosine kinase (IC50 = 42 nM) that displays selectivity over a range of other kinases.
Targets
FLT3
42 nM
In vitro DMSO 14 mg/mL (38.84 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.74 mL 138.72 mL 277.45 mL
0.5 mM 5.55 mL 27.74 mL 55.49 mL
1 mM 2.77 mL 13.87 mL 27.74 mL
5 mM 0.55 mL 2.77 mL 5.55 mL

*The above data is based on the productmolecular weight 360.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12427
Actions Inhibitor
CAS No. 301305-73-7
Formula C18H20N2O4S
M. Wt 360.43
Purity >98%
Synonyms TCS359, TCS-359
SMILES COC1=C(C=C(C=C1)C(=O)NC2=C(C3=C(S2)CCCC3)C(=O)N)OC
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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