Biological Activity
TG 100572 is a multi-targeted kinase inhibitor that inhibit select growth factor receptor tyrosine kinases and Src familt kinases with IC50 values of 2/7/2/1/0.5 nM for VEGFR1/VEGFR2/FGFR1/Src/Fyn kianse respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 19.51 mL | 97.57 mL | 195.15 mL |
0.5 mM | 3.9 mL | 19.51 mL | 39.03 mL |
1 mM | 1.95 mL | 9.76 mL | 19.51 mL |
5 mM | 0.39 mL | 1.95 mL | 3.9 mL |
*The above data is based on the productmolecular weight 512.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15260 |
---|---|
Actions | Inhibitor |
M. Wt | 512.43 |
Formula | C26H27Cl2N5O2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 867331-64-4 |
Synonyms | TG100572 Hydrochloride, TG-100572 Hydrochloride |
SMILES | CC1=C2C(=CC(=C1)C3=C(C=CC(=C3)O)Cl)N=NC(=N2)NC4=CC=C(C=C4)OCCN5CCCC5.Cl |
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