Thalidomide-NH-C2-azaspiro3.5nonane hydrochloride

Catalog No.: A80259
Intermediate
Thalidomide-NH-C2-azaspiro[3.5]nonane hydrochloride serves as a crucial intermediate in the synthesis of IRAK degraders. Its structural properties facilitate the development of compounds that modulate immune responses by targeting IRAK proteins. This reagent is valuable for researchers focusing on therapeutic applications in inflammatory diseases and immune regulation.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-NH-C2-azaspiro[3.5]nonane hydrochloride serves as a crucial intermediate in the synthesis of IRAK degraders. Its structural properties facilitate the development of compounds that modulate immune responses by targeting IRAK proteins. This reagent is valuable for researchers focusing on therapeutic applications in inflammatory diseases and immune regulation.
Product Information
Catalog NumA80259
FormulaC23H29ClN4O4
Molecular Weight460.95
CAS Number2573304-92-2
SMILESO=C1NC(C(N2C(C3=CC=CC(NCCC4CC5(CCNCC5)C4)=C3C2=O)=O)CC1)=O.[H]Cl
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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