Tie2 kinase inhibitor

Catalog No.: A10932

Tie2 kinase inhibitor

Tie2 kinase inhibitor

Tie2 kinase inhibitor Chemical Structure

CAS NO. 948557-43-5

Tie2 kinase inhibitor is a potent and selective Tie2 inhibitor with IC50 of 0.25 μM.

Availability: Out of stock

Package Price
5 mg
$90.00
10 mg
$160.00
50 mg
$450.00
100 mg
$750.00
10mM * 1mL in DMSO
$138.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Tie2 kinase inhibitor is a potent and selective Tie2 inhibitor with IC50 of 0.25 μM.
Targets
Tie-2
0.25 μM
In vitro (25°C) DMSO 35 mg/mL (79.63 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 2% Cremophor EL, 2% N,N-dimethylacetamide 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.75 mL 113.77 mL 227.53 mL
0.5 mM 4.55 mL 22.75 mL 45.51 mL
1 mM 2.28 mL 11.38 mL 22.75 mL
5 mM 0.46 mL 2.28 mL 4.55 mL

*The above data is based on the productmolecular weight 439.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10932
Actions Inhibitor
M. Wt 439.5
Formula C26H21N3O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 948557-43-5
SMILES COC1=CC2=C(C=C1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)S(=O)C)C5=CC=NC=C5

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