Tie2 kinase inhibitor

Catalog No.: A10932

Tie2 kinase inhibitor

Tie2 kinase inhibitor

Tie2 kinase inhibitor Chemical Structure

CAS NO. 948557-43-5

Tie2 kinase inhibitor is a potent and selective Tie2 inhibitor with IC50 of 0.25 μM.

Availability: Out of stock

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5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $160.00

Special Price $128.00

50 mg

Regular Price: $450.00

Special Price $360.00

100 mg

Regular Price: $750.00

Special Price $600.00

10mM * 1mL in DMSO

Regular Price: $138.00

Special Price $110.40

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Biological Activity

Tie2 kinase inhibitor is a potent and selective Tie2 inhibitor with IC50 of 0.25 μM.
Targets
Tie-2
0.25 μM
In vitro (25°C) DMSO 35 mg/mL (79.63 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% Cremophor EL, 2% N,N-dimethylacetamide 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.75 mL 113.77 mL 227.53 mL
0.5 mM 4.55 mL 22.75 mL 45.51 mL
1 mM 2.28 mL 11.38 mL 22.75 mL
5 mM 0.46 mL 2.28 mL 4.55 mL

*The above data is based on the productmolecular weight 439.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10932
Actions Inhibitor
CAS No. 948557-43-5
Formula C26H21N3O2S
M. Wt 439.5
Purity >98%
SMILES COC1=CC2=C(C=C1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)S(=O)C)C5=CC=NC=C5
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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