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TL033

Catalog No.: A41392
Drug-Linker Conjugates For ADC
TL033 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It comprises a linker and a bioactive small molecule toxin, enabling its conjugation with Sacituzumab, an anti-Trop-2 antibody, to synthesize BT001021. BT001021 exhibits anti-cancer activity against various malignancies, including breast cancer, non-small cell lung cancer (NSCLC), and gastric cancer, making it a valuable tool for cancer research and therapeutic development.
TL033 2356230-22-1 Drug-Linker Conjugates For ADC
Grouped product items
Size Price Stock Qty
5mg
$720.00
In stock
10mg
$1,175.00
In stock
25mg
$2,370.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTL033 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It comprises a linker and a bioactive small molecule toxin, enabling its conjugation with Sacituzumab, an anti-Trop-2 antibody, to synthesize BT001021. BT001021 exhibits anti-cancer activity against various malignancies, including breast cancer, non-small cell lung cancer (NSCLC), and gastric cancer, making it a valuable tool for cancer research and therapeutic development.
Product Information
Catalog NumA41392
FormulaC76H103N13O23S2
Molecular Weight1630.83
CAS Number2356230-22-1
SMILESO=C1N2C(C3=NC4=CC=CC=C4C(CCN(C(C)C)S(C)(=O)=O)=C3C2)=CC5=C1COC([C@@]5(CC)OC(OCC6=CC=C(C=C6)NC([C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN7C=C(N=N7)CNC(CCCC#CC8=CN=C(S(C)(=O)=O)N=C8)=O)=O)=O)=O)=O)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC