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Tub114

Catalog No.: A41544
Drug-Linker Conjugate for ADC
Tub114 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound is an analog of Tubulysin B, featuring a stable hydrophilic linker that enhances its suitability for the synthesis of ADCs. Tub114 exhibits key biological activity by selectively targeting and inhibiting tumor cell proliferation, making it a valuable tool for cancer research and therapeutic development.
Tub114 2361406-35-9 Drug-Linker Conjugate for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionTub114 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound is an analog of Tubulysin B, featuring a stable hydrophilic linker that enhances its suitability for the synthesis of ADCs. Tub114 exhibits key biological activity by selectively targeting and inhibiting tumor cell proliferation, making it a valuable tool for cancer research and therapeutic development.
Product Information
Catalog NumA41544
FormulaC76H124N10O24S
Molecular Weight1593.92
CAS Number2361406-35-9
SMILESO=C(C=CC1=O)N1CCCC(N[C@@H](CCCCNC(COCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(NCCCC(NC(C=C2C[C@H](NC(C3=CSC([C@@H](C[C@@H](N(C([C@@H](NC(C(C)(N(C)C)C)=O)[C@H](CC)C)=O)C)C(C)C)OC(C)=O)=N3)=O)C[C@@H](C(O)=O)C)=C(C=C2)O)=O)=O)=O
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This equation is commonly abbreviated as: C1V1 = C2V2

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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC