Type-II-IN-1

Name: Type-II-IN-1
Brand: Adooq Bioscience
SKU: A84743
Rating: 5 (288 reviews)

Catalog No.: A84743

Syk Inhibitor

Type-II-IN-1 is a potent type II inhibitor of spleen tyrosine kinase (Syk), exhibiting an IC50 value of 2.1 nM. It specifically interacts with the DFG-out conformation of Syk, making it a valuable tool for the study of immunological processes. This compound is particularly relevant for research applications related to asthma and other immune-related disorders.

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Biological Activity

Description	Type-II-IN-1 is a potent type II inhibitor of spleen tyrosine kinase (Syk), exhibiting an IC50 value of 2.1 nM. It specifically interacts with the DFG-out conformation of Syk, making it a valuable tool for the study of immunological processes. This compound is particularly relevant for research applications related to asthma and other immune-related disorders.

Product Information

Catalog Num	A84743
Formula	C29H22F3N5O2
Molecular Weight	529.51
CAS Number	1419299-81-2
SMILES	O=C(C1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(C)C(C3=CC4=C(N(C)C3=O)N=C(NC5=CC=CC=C5)N=C4)=C2

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