Tyrosine kinase-IN-1

Catalog No.: A12486

multi-targeted tyrosine kinase inhibitor

Tyrosine kinase-IN-1

Tyrosine kinase-IN-1 Chemical Structure

CAS NO. 705946-27-6

Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor with IC50s of 4, 20, 4, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively.

Availability: In stock

Package Price Qty
10 mg
$54.00
25 mg
$108.00
50 mg
$186.00
100 mg
$318.00
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Biological Activity

Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor with IC50s of 4, 20, 4, 2 nM for KDR, Flt-1, FGFR1 and PDGFRα, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.45 mL 112.23 mL 224.45 mL
0.5 mM 4.49 mL 22.45 mL 44.89 mL
1 mM 2.24 mL 11.22 mL 22.45 mL
5 mM 0.45 mL 2.24 mL 4.49 mL

*The above data is based on the productmolecular weight 445.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12486
Actions Inhibitor
M. Wt 445.53
Formula C26H28FN5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 705946-27-6
SMILES O=C1NC2=C(C=C(NC3CCN(CC)CC3)C=C2)/C1=C(C4=CC=CC(F)=C4)/C5=NC=C(C)N5

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