Catalog No.: A14222
Mcl-1 inhibitor
UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family.
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UMI-77 5mg
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UMI-77 10mg
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UMI-77 25mg
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UMI-77 10mM * 1mL in DMSO
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Biological Activity
Discription UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family.
Target Value
Product Information
Catalog Num A14222
Formula C18H14BrNO5S2
Molecular Weight 468.34
CAS Number 518303-20-3
SMILES C1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=C(C=C3)Br
Synonyms UMI 77,UMI77

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

In vitro (25°C) DMSO 92 mg/mL (196.43 mM)
Water Insoluble
Ethanol Warmed: 92 mg/mL (196.43 mM)
In vivo 5% DMSO+30% PEG 300+dd H2O 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.35 mL 106.76 mL 213.52 mL
0.5 mM 4.27 mL 21.35 mL 42.7 mL
1 mM 2.14 mL 10.68 mL 21.35 mL
5 mM 0.43 mL 2.14 mL 4.27 mL
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