UMI-77

Catalog No.: A14222

Mcl-1 inhibitor

UMI-77

UMI-77 Chemical Structure

CAS NO. 518303-20-3

UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $100.00

Special Price $80.00

10 mg

Regular Price: $160.00

Special Price $128.00

25 mg

Regular Price: $300.00

Special Price $240.00

10mM * 1mL in DMSO
$110.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

UMI-77 is a selective Mcl-1 inhibitor with Ki of 490 nM, showing selectivity over other members of Bcl-2 family.
Targets
Mcl-1
490 nM(Ki)
In vitro DMSO 93 mg/mL (198.57 mM)
Water <1 mg/mL (<1 mM)
Ethanol 93 mg/mL heating (198.57 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.35 mL 106.76 mL 213.52 mL
0.5 mM 4.27 mL 21.35 mL 42.7 mL
1 mM 2.14 mL 10.68 mL 21.35 mL
5 mM 0.43 mL 2.14 mL 4.27 mL

*The above data is based on the productmolecular weight 468.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A14222
Actions Inhibitor
M. Wt 468.34
Formula C18H14BrNO5S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 518303-20-3
Synonyms UMI 77,UMI77
SMILES C1=CC=C2C(=C1)C(=CC(=C2O)SCC(=O)O)NS(=O)(=O)C3=CC=C(C=C3)Br

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