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UNC-2025

Dual MER/FLT3 inhibitor

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Catalog No. A15904

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
UNC-2025 5mg A15904-5
$110.00
UNC-2025 10mg A15904-10
$200.00
UNC-2025 25mg A15904-25
$420.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.

UNC-2025

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Chemical Information

Catalog Num A15904
Actions Inhibitor
M. Wt 513.12
Formula C28H41ClN6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1429881-91-3
Synonyms UNC 2025, UNC-2025
SMILES CN1CCN(CC2=CC=C(C3=CN([[email protected]@H]4CC[[email protected]@H](O)CC4)C5=NC(NCCCC)=NC=C35)C=C2)CC1

Biological Activity

Description
UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.49 mL 97.44 mL 194.89mL
0.5 mM 3.9 mL 19.49 mL 38.98 mL
1 mM 1.95 mL 9.74 mL 19.49 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 513.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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