UNC-2025

Name: UNC-2025
Brand: Adooq Bioscience
SKU: A15904
Rating: 5 (288 reviews)

Catalog No.: A15904

Dual MER/FLT3 inhibitor

UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.

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UNC-2025 1429881-91-3 Dual MER/FLT3 inhibitor

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Grouped product items
Size	Price	Stock
2mg	$25.00	In stock
5mg	$45.00	In stock
10mg	$80.00	In stock
25mg	$120.00	In stock
50mg	$200.00	In stock
100mg	$360.00	In stock
*10mM 1mL in DMSO**	$45.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description

UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A15904
Formula	C28H40N6O
Molecular Weight	476.7
CAS Number	1429881-91-3
SMILES	CCCCNC1=NC=C2C(=CN(C2=N1)C3CCC(CC3)O)C4=CC=C(C=C4)CN5CCN(CC5)C
Synonyms	UNC 2025, UNC-2025
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	88 mg/mL (184.62 mM)
	Water	Insoluble
	Ethanol	53 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.98 mL	104.89 mL	209.78 mL
0.5 mM	4.2 mL	20.98 mL	41.96 mL
1 mM	2.1 mL	10.49 mL	20.98 mL
5 mM	0.42 mL	2.1 mL	4.2 mL

Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂