UNC-2025

Catalog No.: A15904

Dual MER/FLT3 inhibitor

UNC-2025 Chemical Structure

CAS NO. 1429881-91-3

UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $75.00

Special Price $60.00

10 mg

Regular Price: $120.00

Special Price $96.00

25 mg

Regular Price: $250.00

Special Price $200.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

UNC-2025 is a potent and orally bioavailable dual MER/FLT3 inhibitor with IC50 of 0.74 nM and 0.8 nM, respectively, about 20-fold selectivity over Axl and Tyro3.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.49 mL 97.44 mL 194.89 mL
0.5 mM 3.9 mL 19.49 mL 38.98 mL
1 mM 1.95 mL 9.74 mL 19.49 mL
5 mM 0.39 mL 1.95 mL 3.9 mL

*The above data is based on the productmolecular weight 513.12. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15904
Actions Inhibitor
M. Wt 513.12
Formula C28H41ClN6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1429881-91-3
Synonyms UNC 2025, UNC-2025
SMILES CN1CCN(CC2=CC=C(C3=CN([[email protected]@H]4CC[[email protected]@H](O)CC4)C5=NC(NCCCC)=NC=C35)C=C2)CC1

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