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Vat-Cit-PAB-Monomethyl Dolastatin 10

Catalog No.: A41492
Drug-Linker Conjugates For ADC
Vat-Cit-PAB-Monomethyl Dolastatin 10 is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). It utilizes Monomethyl Dolastatin 10, a highly effective tubulin inhibitor, linked through the Vat-Cit-PAB linker to enhance its therapeutic potential. This compound exhibits significant antitumor activity, making it a valuable tool for cancer research and the development of targeted therapies.
Vat-Cit-PAB-Monomethyl Dolastatin 10 1415329-13-3 Drug-Linker Conjugates For ADC
Grouped product items
Size Price Stock Qty
1mg
$145.00
In stock
5mg
$450.00
In stock
10mg
$740.00
In stock
25mg
$1,555.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVat-Cit-PAB-Monomethyl Dolastatin 10 is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). It utilizes Monomethyl Dolastatin 10, a highly effective tubulin inhibitor, linked through the Vat-Cit-PAB linker to enhance its therapeutic potential. This compound exhibits significant antitumor activity, making it a valuable tool for cancer research and the development of targeted therapies.
Product Information
Catalog NumA41492
FormulaC60H93N11O11S
Molecular Weight1176.51
CAS Number1415329-13-3
SMILESCC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N2CCC[C@@H]2[C@H](OC)[C@@H](C)C(N[C@H](C3=NC=CS3)CC4=CC=CC=C4)=O)=O)=O)=O)=O)C=C1)=O)=O
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC