• Sign In
  • FAQ
  • Create an Account
Currency
USD currency flagUSD
Toggle Nav
My Cart
Menu
Account
Settings
Currency
USD currency flagUSD

VcMMAE-Deruxtecan

Catalog No.: A41401
Drug-Linker Conjugate for ADC
VcMMAE-Deruxtecan is a targeted drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound combines a cytotoxic microtubule inhibitor, MMAE, with Exatecan, a DNA topoisomerase I inhibitor, facilitating precise targeting of cancer cells. VcMMAE-Deruxtecan is primarily utilized in the synthesis of ADCs, contributing to advancements in cancer therapeutics.
VcMMAE-Deruxtecan 2760408-75-9 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$735.00
In stock
5mg
$1,885.00
In stock
10mg
$3,065.00
In stock
Bulk Size
Bulk Discount
Bulk Inquiry
Notify me when the price drops
Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionVcMMAE-Deruxtecan is a targeted drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. This compound combines a cytotoxic microtubule inhibitor, MMAE, with Exatecan, a DNA topoisomerase I inhibitor, facilitating precise targeting of cancer cells. VcMMAE-Deruxtecan is primarily utilized in the synthesis of ADCs, contributing to advancements in cancer therapeutics.
Product Information
Catalog NumA41401
FormulaC121H159FN20O28
Molecular Weight2360.67
CAS Number2760408-75-9
SMILESCC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C3=CC=CC=C3)=O)([H])CCC2)=O)C)=O)=O)=O)C=C1)=O)=O)NC(C(NC(CCCCCN4C(C=CC4=O)=O)=O)CC(C=C5)=CC=C5OCC(NCC(NCC(N[C@@H](CC6=CC=CC=C6)C(NCC(NCOCC(N[C@@H]7C8=C9C(C(N%10C9)=CC([C@](O)(C(OC%11)=O)CC)=C%11C%10=O)=NC%12=CC(F)=C(C)C(CC7)=C%128)=O)=O)=O)=O)=O)=O)=O
SynonymsSMP-54418
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC