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XB010 drug-linker

Catalog No.: A41514
Drug-Linker Conjugates for ADC
XB010 drug-linker is a conjugate that combines MMAE with RED-601, specifically designed for the synthesis of antibody-drug conjugates (ADCs). This drug-linker facilitates targeted delivery of cytotoxic agents to cancer cells, enhancing therapeutic efficacy while minimizing off-target effects. Researchers utilize XB010 for the development of ADCs aimed at improving anticancer treatments and studying the mechanisms of drug action in tumor biology.
XB010 drug-linker 2773415-17-9 Drug-Linker Conjugates for ADC
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXB010 drug-linker is a conjugate that combines MMAE with RED-601, specifically designed for the synthesis of antibody-drug conjugates (ADCs). This drug-linker facilitates targeted delivery of cytotoxic agents to cancer cells, enhancing therapeutic efficacy while minimizing off-target effects. Researchers utilize XB010 for the development of ADCs aimed at improving anticancer treatments and studying the mechanisms of drug action in tumor biology.
Product Information
Catalog NumA41514
FormulaC84H130N14O26S
Molecular Weight1784.07
CAS Number2773415-17-9
SMILESCN(NC)CC1=CC2=C(N1CCC(N[C@@H](CS(=O)(O)=O)C(NCCOCCOCCC(N[C@@H](C(C)C)C(N[C@@H](C)C(NC3=CC=C(COC(N(C)[C@H](C(N[C@@H](C(C)C)C(N(C)[C@H]([C@@H](CC(N4[C@]([C@H](OC)[C@H](C(N[C@@H]([C@H](C5=CC=CC=C5)O)C)=O)C)(CCC4)[H])=O)OC)[C@H](CC)C)=O)=O)C(C)C)=O)C=C3O[C@@H]6O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]6O)=O)=O)=O)=O)=O)N=CC=C2
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC